The NIH Library’s Bioinformatics Support Program is presenting a class, MetaCore: Enabling Systems Biology Research through Pathway Analysis, on August 2, from 9:30 a.m. to 4:00 p.m. in the NIH Library Training Room, Building 10. Even if the class is full, please sign up for the waitlist and plan on attending the class. When the class begins, empty seats will be filled on a first-come, first-served basis by waitlisted students who arrive early and sign in. An effort is made to accommodate everyone.
MetaCore is a curated knowledge database and software suite for pathway analysis of experimental data and gene lists. The data types include microarray and sequence-based gene expression, SNPs and CGH arrays, RNAi screens, gene variants, proteomics, metabolomics, Co-IP pull-out, and other custom interactions which can all be analyzed in tandem. MetaCore is based on a high-quality, manually-curated database of transcription factors, receptors, ligands, kinases, drugs, and endogenous metabolites as well as other molecular classes; species-specific directional interactions between protein-protein, protein-DNA and protein-RNA, drug targeting, and bioactive molecules and their effects; signaling and metabolic pathways represented on maps and networks; and rich ontologies for diseases and processes with hierarchical or graphic output.
MetaCore’s analytical package includes intuitive tools for searching and data visualization, enabling the identification of the most relevant biological pathways, networks, and processes. The Genomic Analysis Tools (GAT) help users upload gene variant files, run genotype analyses, filter and annotate variants, and perform downstream analyses of their filtered variants.
For more information on how to access the NIH Library’s MetaCore license, please visit nihlibrary.nih.gov/services/bioinformatics-support/analysis-tools-databases.
For further information about the class and to register, visit: nihlibrary.nih.gov/node/386076/register.
Go to the NIH Library’s Bioinformatics Support Program page to learn more about the program.
Sign language interpreters and other reasonable accommodations can be provided. If you require such accommodations, please contact the NIH Library Information Desk at 301-496-1080 five business days in advance. For TDD users/callers, please call the above number through the Federal Relay Service at 1-800-877-8339.
The NIH Library in Building 10 serves the information needs of NIH staff and select Department of Health and Human Services (HHS) agencies. The NIH Library is part of the Office of Research Services (ORS) in the Office of the Director (OD).