Systematic Review Protocols
- a good systematic review can start with a protocol - it can serve as a road map for your review
- a protocol specifies the objectives, methods, and outcomes of primary interest of the systematic review
- a protocol promotes transparency of methods
- allows your peers to review how you will extract information to quantitavely summarize your outcome data
Sample Protocols
- Boosted Protease Inhibitor (PI) Monotherapy for Treating HIV/AIDS (Protocol)
Jaoko W, Cochrane Database of Systematic Reviews, 2009
- Neuraminidase Inhibitors for Prevention and Treatment of Influenza in Healthy Adults and Children: A Review of Clinical Study Reports. (Protocol)
Jefferson T, et.al., The Cochrane Database of Systematic Reviews_2011
About Systematic Review Registries
- Various protocol registries exists
- Anyone can register their protocol
- Registering your protocol is helpful to establish that your group is doing this review
- Registering increases potential communication with interested researchers
- Registering may reduce the risk of multiple reviews addressing the same question
- Registering may provide greater transparency when updating a systematic review
Systematic Review/Protocol Registries
- Campbell Collaboration - produces systematic reviews of the effects of social interventions
- Cochrane Collaboration - international organization, produces and disseminates systematic reviews of health care interventions
- PROSPERO -international prospective register of systematic reviews
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