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Bias in Research Studies: Publication Bias

Publication bias refers to the phenomenon where studies with statistically significant results are much more likely to be published in peer-refereed journals than studies that report a nonsignificant conclusion. Bias develops when results are pooled from published studies alone, leading to an overestimation of the effectiveness of the intervention. In this presentation we define publication bias, how it affects the results of clinical research literature reviews, how it can be detected and minimized, and how it can be prevented.

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